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Histochemistry and Cell Biology · 2025 · Vol. 163 · Issue 1 · Springer
The role of angiogenesis in preeclampsia pathogenesis is widely studied; however, despite the lymphatic vessels’ complementary role to the blood vascular system, studies on their morphology in the placenta and placental bed are lacking. In total, 87 placental bed specimens were utilized, which were grouped into normotensive pregnant ( n = 28), early-onset preeclampsia ( n = 31), and late-onset preeclampsia ( n = 28), and furth...
Histochemistry and Cell Biology · 2025 · Vol. 163 · Issue 1 · Springer
Preeclampsia, a severe pregnancy complication linked to defective placentation, poses significant maternal risks and is characterized by dysregulated angiogenic factors, including placental growth factor (PlGF) and soluble fms-like tyrosine kinase-1 (sFlt-1). Women with HIV/AIDS and receiving ART may face an increased susceptibility to preeclampsia development due to immunological and angiogenic imbalance. This study investiga...