Acetamiprid (ACE) is a widely used neonicotinoid insecticide with known neurotoxic potential, for which the European Food Safety Authority lowered the acceptable daily intake. Current physiologically-based kinetic (PBK) models lack adequate kinetic data for ACE and its metabolite acetamiprid-N-desmethyl (ACE-DEM). The aim of this study was to generate detailed disposition data for ACE in a controlled volunteer setting to devel...

The safety of using ethanol-based products for hygienic hand disinfection in healthcare workers is controlled by restricting air levels. This raises the question of whether these workers are sufficiently protected against potential dermal absorption. The study aim was to determine the contribution of the dermal route to the total uptake of ethanol. A laboratory-controlled study of 25 sequential alcohol-based-hand-rubs (ABHRs)...

Aim We investigated turnover and richness in Antarctic springtails to understand large‐scale patterns in soil faunal diversity and how these are altered by biological invasions. Location Antarctica and the Southern Ocean Islands. Taxon Collembola (springtails). Methods We developed a database of all springtail species recorded from the Antarctic region. The relationship of species richness and turnover to high‐resolution envir...