Purpose The study examined the acute muscle and systemic physiological responses to a 5v5 small-sided game (SSG) of football in trained female players. Methods Ten trained female football players (age: 24.5 ± 1.9 years, height: 169 ± 5 cm, weight: 67.0 ± 8.0 kg, fat%: 24.8 ± 7.6%) completed four 12-min periods of play (P1-P4) with 4-min passive recovery. Muscle biopsies were obtained from m. vastus lateralis pre- and post-game...

Aim To evaluate the population pharmacokinetics of unbound F-Ara-A (the circulating metabolite of fludarabine) in 211 patients (age range, 0.1–63.4 years) undergoing allogeneic haematopoietic stem cell transplantation conditioning. Methods Total ( n = 2480) and unbound ( n = 1403) F-Ara-A concentrations were measured in blood samples collected at timed intervals after fludarabine doses ranging from 10 to 50 mg/m 2 and infused...

The breakdown of plant material fuels soil functioning and biodiversity. Currently, process understanding of global decomposition patterns and the drivers of such patterns are hampered by the lack of coherent large‐scale datasets. We buried 36,000 individual litterbags (tea bags) worldwide and found an overall negative correlation between initial mass‐loss rates and stabilization factors of plant‐derived carbon, using the Tea...

Climate change models often assume similar responses to temperatures across the range of a species, but local adaptation or phenotypic plasticity can lead plants and animals to respond differently to temperature in different parts of their range. To date, there have been few tests of this assumption at the scale of continents, so it is unclear if this is a large‐scale problem. Here, we examined the assumption that insect taxa...

Global warming is affecting the population dynamics and trophic interactions across a wide range of ecosystems and habitats. Translating these real‐time effects into their long‐term consequences remains a challenge. The rapid and extreme warming period that occurred after the Last Glacial Maximum (LGM) during the Pleistocene–Holocene transition (7–12 thousand years ago) provides an opportunity to gain insights into the long‐te...

The presence of melanin in muscle fillets of farmed salmon represents a considerable quality problem for the salmon industry with major economic concerns. In this study, we have examined the presence of abnormal pigmentation in vaccinated versus unvaccinated Atlantic salmon, S almo salar L ., and evaluated possible differences between diploid and triploid fish. Furthermore, the impact of the smolt production regime at ambient...