Pablo Castillo results 126
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Development and Validation of an ICP-MS/MS Method for Multi-elemental Analysis of Human Hair with Application to Heart FailureNARA Subscribed
Human hair has emerged as a promising non-invasive matrix for assessing long-term exposure to essential and toxic trace elements relevant to cardiovascular disease. However, its clinical applicability depends on the availability of robust and fully validated analytical methodologies capable of overcoming matrix-related challenges. This study aimed to develop and validate a reliable and high-throughput method for multi-elementa...
Aims The olive tree is a major crop in Mediterranean countries, but its cultivation faces growing challenges due to climate change. Nematophagous fungi are considered key components of soil ecosystems and can potentially control plant-parasitic nematode populations. This study aims to explore the diversity of these fungi in Mediterranean olive groves, assess their potential for controlling plant-parasitic nematodes, and identi...
Purpose Systematic collection and analysis of antimicrobial resistance data from key bacterial pathogens is essential to contribute to control antimicrobial resistance (AMR). The aim of this work was to survey the drug resistance on clinically relevant organisms stratified according to age, gender, clinical specimens and facilities. Methods Microbiological data were collected from 55 centers across 24 states in Mexico between...
CEB-01 membrane loaded with SN-38 for local post-resection control and metastasis reduction in preclinical pancreatic cancer modelsNARA Subscribed
Pancreatic cancer (PC) is an aggressive malignancy with extremely poor prognosis, in which resection surgery remains the only therapeutic option with curative intent. Patients often present with locoregional metastases in lymph nodes, peritoneum and liver at diagnosis (~ 50–60% of patients), precluding the possibility of surgical resection. In addition, majority of patients develop tumor recurrence after surgery, which can be...
Hyperthermia and Early Growth of Cerebral Infarct: The Potential Role of Blood–Brain Barrier PermeabilityNARA Subscribed
Hyperthermia within the first 24 h following ischemic stroke (IS) has been associated with poor outcomes. We sought to determine whether blood–brain barrier (BBB) permeability contributes to the relationship between hyperthermia and early infarct growth (EIG). A retrospective analysis was conducted on a prospective stroke biobank. EIG was defined as the percentage difference between the initial volume (mL) determined by the di...
The genus Xiphinema Cobb, 1913 belongs to the family Longidoridae and consists of approximatelly 280 described species of plant-root ectoparasites. They occur on all continents except Antarctica and many species are important pests of crops, harming plants either by direct parasiting or by vectoring of nepoviruses. Due to their economic importance, several species were subjected to regulations aimed to limit their global sprea...
Epidemiological studies focusing on metal(oid) exposure and excess body weight among children show inconsistent results and the influence of metal(loid) mixtures has been little studied. We aimed to explore the effect of 10 metal(loid)s, individually and in combinations, on overweight and obesity among children aged 6–12. Urinary levels of these metal(oid)s from 92 controls and 51 cases with overweight and obesity were analyze...