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Major-element, trace-element and sulfur-isotope evidence for arc-like magmatism in the 4.0–2.9 Ga Acasta Gneiss ComplexNARA Subscribed
The Acasta Gneiss Complex (AGC) in northwestern Canada comprises Earth’s oldest known evolved crust, with zircon U–Pb ages up to 4.03 Ga. Several pulses of crustal generation and metamorphism are preserved in tonalitic and granitic gneisses spanning over one billion years, along with mafic and ultramafic rocks of unknown age. Major elements, trace elements and radiogenic isotope signatures have been invoked to suggest that the...
The impact of waves, storm surge, and aeolian transport associated with Post-tropical Storm Fiona (offshore significant wave height ∽ 8 m, storm surge up to 2 m) on the sandy beaches and foredunes of the north shore of Prince Edward Island National Park (PEINP), Canada, are assessed. Management policies and practices, as they apply to sandy beach systems within PEINP, are reviewed in the context of the shoreline changes attrib...
Drug Dissolution in Oral Drug Absorption: Workshop ReportNARA Subscribed
The in-person workshop “Drug Dissolution in Oral Drug Absorption” was held on May 23–24, 2023, in Baltimore, MD, USA. The workshop was organized into lectures and breakout sessions. Three common topics that were re-visited by various lecturers were amorphous solid dispersions (ASDs), dissolution/permeation interplay, and in vitro methods to predict in vivo biopharmaceutics performance and risk. Topics that repeatedly surfaced...
SCAview: an Intuitive Visual Approach to the Integrative Analysis of Clinical Data in Spinocerebellar AtaxiasNARA Subscribed
With SCAview, we present a prompt and comprehensive tool that enables scientists to browse large datasets of the most common spinocerebellar ataxias intuitively and without technical effort. Basic concept is a visualization of data, with a graphical handling and filtering to select and define subgroups and their comparison. Several plot types to visualize all data points resulting from the selected attributes are provided. The...
Implications of climate change mitigation strategies on international bioenergy tradeNARA Subscribed
Most climate change mitigation scenarios rely on increased use of bioenergy to decarbonize the energy system. Here we use results from the 33rd Energy Modeling Forum study (EMF-33) to investigate projected international bioenergy trade for different integrated assessment models across several climate change mitigation scenarios. Results show that in scenarios with no climate policy, international bioenergy trade is likely to i...
Metabolism of halophilic archaeaNARA Subscribed
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