Neurons form the basic anatomical and functional structure of the nervous system, and defects in neuronal differentiation or formation of neurites are associated with various psychiatric and neurodevelopmental disorders. Dynamic changes in the cytoskeleton are essential for this process, which is, inter alia, controlled by the dedicator of cytokinesis 4 ( DOCK4 ) through the activation of RAC1 . Here, we clinically describe 7...

In 2017, hurricane Maria caused unprecedented damage and fatalities on the Caribbean island of Dominica. In order to ‘build back better’ and to learn from the processes causing the damage, it is important to quickly document, evaluate and map changes, both in Dominica and in other high-risk countries. This paper presents an innovative and relatively low-cost and rapid workflow for accurately quantifying geomorphological change...

Aim Bergmann's rule, one of the most studied and controversial ecogeographical generalizations, has rarely been tested with observations from high latitudes. We tested the rule using cranial measurements of the muskox [ Ovibos moschatus (Zimmerman)], a homeotherm with an extremely northern distribution. We also used these data to describe geographical patterns in the species' dental architecture, an extension of the framework...