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NARA Subscribed2
Publisher
Springer Nature2
Journal
GeroScience1
Molecular Neurobiology1
Publication Year
20202
Pavithra Premkumar results 2 · Newest (Page 1/1, per page 25)
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Molecular changes associated with spinal cord agingNARA Subscribed
GeroScience · 2020 · Vol. 42 · Issue 2 · Springer
Katarzyna M. Piekarz; Shylesh Bhaskaran; Kavithalakshmi Sataranatarajan; Kaitlyn Street; Pavithra Premkumar; Debra Saunders; Michelle Zalles; Rafal Gulej; Shadi Khademi; Jaime Laurin; Rick Peelor; Benjamin F. Miller; Rheal Towner; Holly Van Remmen
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Disparate Central and Peripheral Effects of Circulating IGF-1 Deficiency on Tissue Mitochondrial FunctionNARA Subscribed
Molecular Neurobiology · 2020 · Vol. 57 · Issue 3 · Springer
Gavin Pharaoh; Daniel Owen; Alexander Yeganeh; Pavithra Premkumar; Julie Farley; Shylesh Bhaskaran; Nicole Ashpole; Michael Kinter; Holly Van Remmen; Sreemathi Logan
Age-related decline in circulating levels of insulin-like growth factor (IGF)-1 is associated with reduced cognitive function, neuronal aging, and neurodegeneration. Decreased mitochondrial function along with increased reactive oxygen species (ROS) and accumulation of damaged macromolecules are hallmarks of cellular aging. Based on numerous studies indicating pleiotropic effects of IGF-1 during aging, we compared the central...
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