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A comparison of pharmacometric software programs for atezolizumab population pharmacokinetic simulationNARA Subscribed
Purpose We compare our experience with three pharmacometric modeling workflows for simulating alternative dosing regimens of atezolizumab: (1) the gold-standard, NONMEM software used in combination with R, (2) the R-based package RxODE, and (3) the recently developed Julia-based software Pumas, discussing the advantages and limitations of each. Methods Our prior work demonstrated that an extended-interval dosing regimen (840 m...
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