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Dapagliflozin attenuates hepatic steatosis and induces a fasting-mimicking metabolic state in C57BL/6 miceNARA Subscribed
Metabolic steatotic liver disease (MASLD) lacks effective pharmacological therapies targeting mitochondrial dysfunction, a central driver of disease progression. We hypothesized that dapagliflozin attenuates MASLD progression by promoting an indirect systemic fasting-mimicking state, thereby proposing the hypothesis of mitochondrial restoring mitochondrial bioenergetics restoration via modulation of the SIRT1–PGC-1α signaling...
The collaboration between Cabo Verdean and German institutions in marine sciences began in 2004. Since then, it has evolved from project-based ocean observation efforts to a sustained, long-term partnership with strong commitments from both countries. Today, research infrastructure such as the Cape Verde Ocean Observatory and the Ocean Science Centre Mindelo, as well as the international master’s program, Climate Change and Ma...
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