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Gas transport dynamics at Kolumbo submarine volcano: high-resolution numerical simulations, scaling laws, and hazard implicationsNARA Subscribed
The 1650 CE Kolumbo (Greece) submarine eruption resulted in the reported deaths of 50 people and thousands of animals on Santorini (Thera) due to exposure to a cloud of noxious volcanic gases. Lack of ash in the cloud indicates that the gas release was unrelated to a magmatic explosive eruption. Medical evidence from historic accounts suggests lethal exposure to CO 2 and H 2 S, which were likely the main hazardous gases, where...
Future eruptions of the Kolumbo volcanic field: prognosis with hazard and risk assessmentNARA Subscribed
The Kolumbo submarine volcanic field consists of at least 24 monogenetic cones and a polygenetic central volcano which erupted in 1650 CE. The prognosis, hazards and risks from future eruptions are assessed by structured expert judgement informed by knowledge of the volcanic history, structure and eruptive products, hazards modelling and global knowledge of submarine volcanism. There are significant knowledge gaps leading to l...
The Kolumbo volcanic field, Greece: a review of evidence to reconstruct the 1650 CE eruption and to support hazard and risk assessmentNARA Subscribed
The Kolumbo volcanic field, Aegean Sea, Greece, consists of at least 25 monogenetic submarine volcanic cones and a polygenetic central volcano which had a VEI 5 rhyolitic explosive eruption in 1650 CE. The present-day polygenetic volcano is characterized by a zone of heightened seismicity at 4 to 9 km depth, a geophysically imaged magma chamber at 2–4 km depth and a shallower, hydrothermal system discharging CO 2 -rich fluids...
Germline copy number variants and endometrial cancer riskNARA Subscribed
Known risk loci for endometrial cancer explain approximately one third of familial endometrial cancer. However, the association of germline copy number variants (CNVs) with endometrial cancer risk remains relatively unknown. We conducted a genome-wide analysis of rare CNVs overlapping gene regions in 4115 endometrial cancer cases and 17,818 controls to identify functionally relevant variants associated with disease. We identif...
The STORMTOOLS Coastal Environmental Risk Index (CERI) has historically been used to assess the damage to residential and commercial structures from coastal flooding, including the effects of sea level rise (SLR) in RI. In the present study, CERI was extended to address the impact of flooding for 100 yr storm, including the effects of SLR, to the newly renovated Warren, RI wastewater treatment facilities (WWTF), located on the...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
Volcanic air pollution from both explosive and effusive activity can affect large populations as far as thousands of kilometers away from the source, for days to decades or even centuries. Here, we summarize key advances and prospects in the assessment of health hazards, effects, risk, and management. Recent advances include standardized ash assessment methods to characterize the multiple physicochemical characteristics that m...
Assessing the biological reactivity of organic compounds on volcanic ash: implications for human health hazardNARA Subscribed
Exposure to volcanic ash is a long-standing health concern for people living near active volcanoes and in distal urban areas. During transport and deposition, ash is subjected to various physicochemical processes that may change its surface composition and, consequently, bioreactivity. One such process is the interaction with anthropogenic pollutants; however, the potential for adsorbed, deleterious organic compounds to direct...
Invasive non‐native species likely to threaten biodiversity and ecosystems in the Antarctic Peninsula regionNARA Subscribed
The Antarctic is considered to be a pristine environment relative to other regions of the Earth, but it is increasingly vulnerable to invasions by marine, freshwater and terrestrial non‐native species. The Antarctic Peninsula region (APR), which encompasses the Antarctic Peninsula, South Shetland Islands and South Orkney Islands, is by far the most invaded part of the Antarctica continent. The risk of introduction of invasive...
Summary Contamination poses a significant problem to the circular economy (CE), which derives much of its value from maintaining pure material flows. The aim of this article is to frame contaminated interaction among other forms of contamination and investigate its effects on the CE. The research is based on a review of the contamination literature and case studies. We differentiate between three types of contamination influen...
The 2010 biodiversity target agreed by signatories to the Convention on Biological Diversity directed the attention of conservation professionals toward the development of indicators with which to measure changes in biological diversity at the global scale. We considered why global biodiversity indicators are needed, what characteristics successful global indicators have, and how existing indicators perform. Because monitoring...