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Despite extensive research on the western Pacific crown-of-thorns starfish (CoTS; Acanthaster cf. solaris ), especially from Australia’s Great Barrier Reef (GBR), there are persistent knowledge gaps that constrain understanding and management. Given renewed population irruptions of CoTS on the GBR, alongside escalating climate impacts and direct anthropogenic pressures, a quantitative assessment of knowledge gaps was undertake...
Aim Australia's arid and semi‐arid zones cover about 70% of the continent, yet our understanding of the biogeography of these diverse and expansive landscapes remains limited. Mulgara ( Dasycercus spp.; Marsupialia: Dasyuridae), a widely distributed mammal taxon, offers an opportunity to explore patterns of the population structure across the region, previously hampered by taxonomic confusion surrounding extant species. Here,...
Imaging studies of FTD typically present group-level statistics between large cohorts of genetically, molecularly or clinically stratified patients. Group-level statistics are indispensable to appraise unifying radiological traits and describe genotype-associated signatures in academic studies. However, in a clinical setting, the primary objective is the meaningful interpretation of imaging data from individual patients to ass...
Pharmacological inhibition of MERTK induces in vivo retinal degeneration: a multimodal imaging ocular safety assessmentNARA Subscribed
The receptor tyrosine kinase, MERTK, plays an essential role in homeostasis of the retina via efferocytosis of shed outer nuclear segments of photoreceptors. The Royal College of Surgeons rat model of retinal degeneration has been linked to loss-of-function of MERTK, and together with the MERTK knock-out mouse, phenocopy retinitis pigmentosa in humans with MERTK mutations. Given recent efforts and interest in MERTK as a potent...
Chronic kidney disease of unknown origin is associated with environmental urbanisation in Belfast, UKNARA Subscribed
Chronic kidney disease (CKD), a collective term for many causes of progressive renal failure, is increasing worldwide due to ageing, obesity and diabetes. However, these factors cannot explain the many environmental clusters of renal disease that are known to occur globally. This study uses data from the UK Renal Registry (UKRR) including CKD of uncertain aetiology (CKDu) to investigate environmental factors in Belfast, UK. Ur...
Motivation The BioTIME database contains raw data on species identities and abundances in ecological assemblages through time. These data enable users to calculate temporal trends in biodiversity within and amongst assemblages using a broad range of metrics. BioTIME is being developed as a community‐led open‐source database of biodiversity time series. Our goal is to accelerate and facilitate quantitative analysis of temporal...
A synoptic climatology of strong along‐channel winds on the Coast of British Columbia, CanadaNARA Subscribed
A synoptic climatology using mean sea level pressure and 500‐ hPa geopotential height composites is conducted for strong along‐channel winds that occur through five of the channels dissecting British Columbia's coast. Seasonal (winter, summer) and directional (inflow, air moving from the coast inland; outflow, air moving from inland towards the coast) partitioning of the winds, results in four distinct along‐channel winds that...
Large‐scale, multidirectional larval connectivity among coral reef fish populations in the Great Barrier Reef Marine ParkNARA Subscribed
Larval dispersal is the key process by which populations of most marine fishes and invertebrates are connected and replenished. Advances in larval tagging and genetics have enhanced our capacity to track larval dispersal, assess scales of population connectivity, and quantify larval exchange among no‐take marine reserves and fished areas. Recent studies have found that reserves can be a significant source of recruits for popul...
Genome-wide association study of endometrial cancer in E2C2NARA Subscribed
Contributory presentations/postersNARA Subscribed
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