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Genetic Diversity Is Not Correlated With Species Diversity: A Multispecies Study in a Continental Habitat Island SystemNARA Subscribed
Aim It has been proposed that species diversity (SD) and genetic diversity (GD) co‐vary across natural communities because both are shaped by processes such as immigration and drift. However, empirical reports are contradictory, and multispecies studies are rare. Here we test the hypothesis that the two diversity measures do not correlate in systems with high levels of immigration stochasticity and little GD caused by strong g...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Alkylation of rabbit muscle creatine kinase surface methionine residues inhibits enzyme activity in vitroNARA Subscribed
Creatine kinase (CK) catalyzes the formation of phosphocreatine from adenosine triphosphate (ATP) and creatine. The highly reactive free cysteine residue in the active site of the enzyme (Cys 283 ) is considered essential for the enzymatic activity. In previous studies we demonstrated that Cys 283 is targeted by the alkylating chemical warfare agent sulfur mustard (SM) yielding a thioether with a hydroxyethylthioethyl (HETE)-m...
Large uncertainty in carbon uptake potential of land‐based climate‐change mitigation effortsNARA Subscribed
Most climate mitigation scenarios involve negative emissions, especially those that aim to limit global temperature increase to 2°C or less. However, the carbon uptake potential in land‐based climate change mitigation efforts is highly uncertain. Here, we address this uncertainty by using two land‐based mitigation scenarios from two land‐use models ( IMAGE and MA g PIE ) as input to four dynamic global vegetation models ( DGVM...
Identifying pathways to visions of future land use in EuropeNARA Subscribed
Assessing uncertainties in land cover projectionsNARA Subscribed
Understanding uncertainties in land cover projections is critical to investigating land‐based climate mitigation policies, assessing the potential of climate adaptation strategies and quantifying the impacts of land cover change on the climate system. Here, we identify and quantify uncertainties in global and European land cover projections over a diverse range of model types and scenarios, extending the analysis beyond the ag...
Hotspots of uncertainty in land‐use and land‐cover change projections: a global‐scale model comparisonNARA Subscribed
Model‐based global projections of future land‐use and land‐cover ( LULC ) change are frequently used in environmental assessments to study the impact of LULC change on environmental services and to provide decision support for policy. These projections are characterized by a high uncertainty in terms of quantity and allocation of projected changes, which can severely impact the results of environmental assessments. In this stu...
The Greenland ice core from NorthGRIP (NGRIP) contains a proxy climate record across the Pleistocene–Holocene boundary of unprecedented clarity and resolution. Analysis of an array of physical and chemical parameters within the ice enables the base of the Holocene, as reflected in the first signs of climatic warming at the end of the Younger Dryas/Greenland Stadial 1 cold phase, to be located with a high degree of precision. T...
Aim Carex atrofusca has an arctic–alpine distribution in the Northern Hemisphere, with only a few, disjunct localities known in the European Alps. These alpine populations are declining in number and size. In contrast, C. atrofusca has a wide circumpolar distribution range and is abundant in large parts of the Arctic. The degree of genetic differentiation of the alpine populations and their importance for the conservation of t...
A reevaluation of previously published analyses of stable carbon isotope fractionation by batch cultures of Thalassiosira pseudonana and Emiliania huxleyi indicates that the Rayleigh distillation model was used to model δ 13 C uptake incorrectly. Correct use of the model shows that the relationship between the δ 13 C of the particulate organic carbon (δ p ) and the concentration of the dissolved inorganic carbon (DIC) at the t...
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