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Fire, an important element of human land use strategies, was part of many early industrial activities but also of burning incidents that significantly impacted settlement structures and development. The spatial proximity of the historically well-documented medieval town and sediment archive deposited in its central lake (Stadtsee) was taken to investigate the interplay of fire and socio-environmental developments during the pr...
Modernizing persistence–bioaccumulation–toxicity (PBT) assessment with high throughput animal-free methodsNARA Subscribed
The assessment of persistence (P), bioaccumulation (B), and toxicity (T) of a chemical is a crucial first step at ensuring chemical safety and is a cornerstone of the European Union’s chemicals regulation REACH (Registration, Evaluation, Authorization, and Restriction of Chemicals). Existing methods for PBT assessment are overly complex and cumbersome, have produced incorrect conclusions, and rely heavily on animal-intensive t...
(Re)Conceptualizing decision-making tools in a risk governance framework for emerging technologies—the case of nanomaterialsNARA Subscribed
The utility of decision-making tools for the risk governance of nanotechnology is at the core of this paper. Those working in nanotechnology risk management have been prolific in creating such tools, many derived from European FP7 and H2020-funded projects. What is less clear is how such tools might assist the overarching ambition of creating a fair system of risk governance. In this paper, we reflect upon the role that tools...
E 551, also known as synthetic amorphous silica (SAS), is the second most produced food additive. However, according to the re-evaluation of E 551 by the European Food Safety Authority (EFSA) in 2018, the amount of available data on the oral toxicity of food grade E 551 is still insufficient for reliable risk assessment. To close this gap, this study aimed to investigate six food-grade SAS with distinct physicochemical propert...
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