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Design and Biomechanical Evaluation of a Disposable Eccentric Curette for Effective Necrotic Bone Removal in Core Decompression SurgeryNARA Subscribed
Purpose Osteonecrosis of the femoral head (ONFH) requires effective removal of necrotic tissue to improve surgical outcomes. Conventional curettes often fail to address clinical needs due to limitations in cutting capability, strength, and adaptability. This study introduces a disposable multi-angle eccentric curette designed to enhance necrotic bone removal during core decompression surgery. Methods The curette was designed w...
Background Infections caused by Klebsiella pneumoniae are common and result in high mortality rates. In vitro studies demonstrated the potency of cefoperazone/sulbactam (CPZ/SUL) against Klebsiella pneumoniae . However, the clinical efficacy of CPZ/SUL for the treatment of K. pneumoniae bacteremia has not been studied. Objectives This study aimed to associate the clinical outcomes of patients with bacteremia with the minimal i...