Mycophenolic acid (MPA), the active moiety of both mycophenolate mofetil (MMF) and enteric-coated mycophenolate sodium (EC-MPS), serves as a primary immunosuppressant for maintaining solid organ transplants. Therapeutic drug monitoring (TDM) enhances treatment outcomes through tailored approaches. This study aimed to develop an evidence-based guideline for MPA TDM, facilitating its rational application in clinical settings. Th...

This study explored how the human cortical folding pattern composed of convex gyri and concave sulci affected single-subject morphological brain networks, which are becoming an important method for studying the human brain connectome. We found that gyri-gyri networks exhibited higher morphological similarity, lower small-world parameters, and lower long-term test-retest reliability than sulci-sulci networks for cortical thickn...

Forecasting typhoon waves during typhoons is crucial. In this paper, the numerical wave model SWAN was enhanced through integration with two machine learning methods: the Back Propagation Neural Network and Random Forest. This integration facilitated the development of two distinct models, namely SWAN-BP and SWAN-Tree. Through correlation analysis, key input features were identified for the machine learning models. The forecas...