R. -R. Wu results 31
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Marine ranching has been proposed as a promising solution to manage the depleted coastal fishery ecosystem in recent decades across China. Marine ranching integrates the practices of artificial habitat-based with aquaculture-based enhancement. Assessing the ecological carrying capacity of target species for enhancement is a precondition for determining the optimal numbers for release, particularly for those species whose habit...
Key message We investigate the genetic basis of panicle architecture in switchgrass in two mapping populations across a latitudinal gradient, and find many stable, repeatable genetic effects and limited genetic interactions with the environment. Abstract Grass species exhibit large diversity in panicle architecture influenced by genes, the environment, and their interaction. The genetic study of panicle architecture in perenni...
Size scaling of sea turtle reproduction may reconcile fundamental ecology and conservation strategies at the global scaleNARA Subscribed
Aim The body size of marine megafauna can influence population dynamics because larger females have disproportionally greater reproductive output. We explored how this size scaling relationship can affect predictions of population size structure in nesting sea turtles by combining a phylogenetically controlled meta‐analysis with a long‐term field nesting survey. Location Global (meta‐analysis) and Malaysia (field survey). Time...
While delivery of chemotherapeutics to cancer cells by nanomedicines can improve therapeutic outcomes, many fail due to the low drug loading (DL), poor cellular uptake and endosomal entrapment. This study investigated the potential to overcome these limitations using pH-sensitive liposomes (PSL) empowered by the use of calcium acetate. An acidic dinitrobenzamide mustard prodrug SN25860 was used as a model drug, with non pH-sen...
Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volumeNARA Subscribed
The concept of age acceleration, the difference between biological age and chronological age, is of growing interest, particularly with respect to age-related disorders, such as Alzheimer’s Disease (AD). Whilst studies have reported associations with AD risk and related phenotypes, there remains a lack of consensus on these associations. Here we aimed to comprehensively investigate the relationship between five recognised meas...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
As global change alters the composition and productivity of ecosystems, the importance of subsidies from one habitat to another may change. We experimentally manipulated black mangrove ( Avicennia germinans ) cover in 10 large plots and over a 5‐year period (2014–2019) quantifying the effects of mangrove cover on subsidies of floating organic material (wrack) into coastal wetlands. As mangrove cover increased from 0% to 100%,...