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Integrating genome-wide and epigenome-wide associations for antipsychotic induced extrapyramidal side effectsNARA Subscribed
Rationale Antipsychotic medications are the first-line treatment for schizophrenia. Around 40% of people who are treated with antipsychotics could develop extrapyramidal side-effects (EPSE) including: (1) Dyskinesia, (2) Parkinsonism, (3) Akathisia, and (4) Dystonia. Objectives This study aimed to identify genetic risk factors for EPSE presence following antipsychotic treatment. Methods We conducted Genome-wide association (GW...
The Asia region harbors exceptional chondrichthyan (shark, ray, and chimaera) diversity but faces intense fishing pressure. The Important Shark and Ray Areas (ISRA) process provides a collaborative, evidence-based framework to identify critical habitats and inform spatial management. We assessed ISRAs across the Bay of Bengal, Southeast Asia, and the Northwest Pacific to characterize their extent, ecological significance, and...
Greenhouse gas (GHG) emissions from coastal aquaculture are an emerging environmental concern, with implications for ecosystem sustainability and climate mitigation. In this preliminary field-based study, we quantified carbon dioxide (CO 2 ), methane (CH 4 ), and nitrous dioxide (N 2 O) fluxes from 35 randomly selected prawn farms in coastal Bangladesh, at a single time point using the floating chamber method, with concurrent...