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COVID-19 vaccination shifts neutrophils toward a mixed activated and regulatory phenotype in patients with severe diseaseNARA Subscribed
Background Dysregulation of the innate immune response to SARS-CoV-2 has been linked to poor outcomes in COVID-19. Neutrophils are key players in this response, displaying distinct functional profiles associated with disease severity. This study investigates how neutrophil phenotypes, and their mediators are modulated in severe COVID-19 following vaccination. Methods and Results We conducted an observational case-control study...
Exercise elicits mitonuclear protein imbalance and UPRmt in the liver of mice with obesityNARA Subscribed
Mitochondrial dysfunction plays a critical role in the development of metabolic dysfunction-associated steatotic liver disease (MASLD). It has been proposed that mitochondrial unfolded-protein response (UPR mt ) activation improves mitochondrial function in the liver. Growing evidence demonstrates that physical exercise effectively prevents and treats MASLD. However, the effects of exercise on UPR mt activation in the liver ar...
Essential oil of ocimum gratissimum as a natural fungicide against pathogenic fungi of fruit crops and molecular docking studiesNARA Subscribed
Fungal diseases in fruit crops compromise productivity even when synthetic fungicides are applied. However, growing health and environmental concerns have made such products less attractive to consumers. In this context, the present study aimed to extract and characterise the essential oil (EO) from leaves and flowers of African basil ( Ocimum gratissimum L.) by hydrodistillation and to evaluate its bioactivity against the fun...
This paper presents a framework for automatically generating interpretable LoD2 indoor 3D models from unstructured point clouds. The method treats indoor modeling as a cartographic generalization problem, introducing a 3D corpus of geospatial feature classes that represents indoor environments as parsimonious compositions of geometric primitives organized by spatial grammar and compatible with IndoorGML. A sparse convolutional...
Intestinal Histomorphometric Alterations During Experimental Strongyloidiasis in Mice Treated with Rosmarinus officinalis Essential OilNARA Subscribed
Purpose Strongyloidiasis is an intestinal helminthiasis that can induce structural alterations in the intestinal mucosa during infection. The present study evaluated histomorphometric alterations of the small intestine in mice experimentally infected with Strongyloides venezuelensis and treated with Rosmarinus officinalis essential oil. Methods Infected animals were treated orally with R. officinalis essential oil (200 or 400...
The Asian Green Mussel Perna viridis in the Canal do Itajurú, Brazil: Establishment in a Hypersalinity-Influenced Coastal ChannelNARA Subscribed
The Asian green mussel, Perna viridis , is a globally successful invasive bivalve first recorded in the South Atlantic in 2018. Here, we report and characterize the establishment of P. viridis in the Canal do Itajurú, a coastal channel connecting the hypersaline Araruama Lagoon to the Atlantic Ocean in Rio de Janeiro, Brazil. We assessed its spatial distribution, substrate association, and morphometric variation to evaluate lo...
Histochemical and histometrical changes induced by the rust fungi Kuehneola uredinis in distinct blackberry (Rubus spp.) cultivarsNARA Subscribed
Pathogenic fungi that cause rust adversely affect plants, including crops, affecting them differentially depending on the cultivar. This is the case of blackberry ( Rubus spp.), a member of Rosaceae, introduced in Brazil by Embrapa during the 1980s and 1990s. Given the advantageous nutritional properties of its fruits and the relatively low management costs associated with its cultivation, blackberry production has emerged as...