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Assessment of Salinity Tolerance in Lepeophtheirus salmonis Following Five Generations of Freshwater Treatment SelectionNARA Subscribed
Non‐medicinal approaches for controlling sea lice ( Lepeophtheirus salmonis ) infestations, such as freshwater (FW) treatments, have been increasingly implemented to support more sustainable parasite control in aquaculture. This study evaluated the efficacy of FW treatment against sea lice under controlled experimental conditions and assessed the potential development of resistance across multiple generations. Sea lice populat...
Urbanization exacerbates water scarcity by increasing demand while reducing the availability of natural water reserves. Food waste is another critical issue that affects urban sustainability. Recycling treated greywater presents a sustainable alternative, particularly for irrigation purposes. This study evaluated the effectiveness of a media blend of spent coffee grounds and date seeds (1:2 ratio) for cultivating five ornament...
The aetiology of frailty remains unknown. It has been hypothesised that individual differences in epigenetic mechanisms, particularly DNA methylation (DNAm), may help to explain why some individuals become frail while others do not. Relating epigenetic measures to transitions in age-related frailty in individual patients requires longitudinal studies over many years. To overcome this barrier, we study associations between DNAm...
Discovery of a Potent Small Molecule Antagonist of GRPR for the Treatment of PruritusNARA Subscribed
Persistent pruritus (itch) affects the quality of life, and many itch syndromes remain untreatable. Previously, we identified the gastrin-releasing peptide receptor (GRPR) playing a critical role in mediating histamine-independent itch signaling. In this study, we aimed to identify small-molecule GRPR antagonists to treat histamine-independent itch. Starting with the known small-molecule GRPR antagonist PD 176,252, we conducte...
Modeling of gene regulatory networks: an annotated glossaryNARA Subscribed
Species‐specific interactions with apex carnivores yield unique benefits and burdens for mesocarnivoresNARA Subscribed
Mesocarnivores navigate a complex risk–reward continuum in ecosystems shared with their apex counterparts, balancing scavenging opportunities with risks of mortality. However, the risks to mesocarnivores in multi‐carnivore systems are not uniform; they can vary with specific apex–meso pairings. Using remote cameras and GPS‐telemetry, we examined space‐use, temporal activity, fine‐scale interactions, and scavenging behaviors of...
Dreissenid mussels represent two of the most problematic invasive species in the Laurentian Great Lakes yet little is known regarding the biochemical and nutritional composition of the veliger larval stage. Here, we quantified energy densities and fatty acids (FA) in veligers as metrics of nutritional quality relative to those determined for three size fractions of crustacean zooplankton collected from Lake Huron's Saginaw Bay...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
Exploring Marine Mammal Cognition as a Conservation ToolNARA Subscribed
Cognition is an animal's real‐time adaptation system for responding to change. Rapid environmental change, often anthropogenic, is expanding the range and severity of challenges confronting wild animals. Effective conservation requires a multifaceted approach that includes animals' capacities. Large‐brained, long‐lived animals such as marine mammals often have extensive capability to adaptively modify their behavior due to the...