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Regulation of PDGF-BB signaling in placental pericytes by soluble PDGFRβ isoforms: implications for fetoplacental vascular developmentNARA Subscribed
Vascular remodeling within the developing fetus and placenta is essential for supporting the growth and function of emerging tissues and organs. Pericytes (PCs) play a central role in stabilizing and maturing microvascular networks by extending along endothelial cells (ECs) and reinforcing vessel integrity. In the placenta, as in other organs, PC–EC communication is mediated in part by platelet-derived growth factor-BB (PDGF‑B...
Warm-season cover crops can reduce nitrogen (N) leaching, build soil organic matter (SOM), and provide N to subsequent cash crops, but the extent of these functions in northern climates remains unknown. We evaluated these ecosystem functional responses to cover crop quantity and quality in contrasting northern US soil types. Cover crop single species (buckwheat, sunn hemp) and bicultures (chickling vetch/sudex and cowpea/sudex...
To examine dimensional associations between anxiety- and depression-related symptom severity, pain catastrophizing, and resting-state EEG features in patients with knee osteoarthritis (KOA). Resting-state EEG spectral power (delta, theta, alpha, beta) was analysed in 62 KOA patients from the DEFINE cohort. Emotional symptoms were assessed with the Hospital Anxiety and Depression Scale (HADS), along with the Pain Catastrophizin...
Modeling of gene regulatory networks: an annotated glossaryNARA Subscribed
Diversity and functional group composition drive biogeographic patterns in marine biogenic structural complexityNARA Subscribed
Biogenic structural complexity is a key driver of biodiversity and ecosystem functioning, yet its ecological and environmental determinants remain poorly understood across broad biogeographic scales. Here, we conducted standardized 90‐day field experiments at 16 coastal sites, spanning a 41‐degree latitudinal gradient, using naturally assembled marine fouling communities on settlement panels. We measured rugosity as our metric...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Non-native rusa deer ( Cervus timorensis ) were introduced to the 380-ha Wild Duck Island, an important flatback turtle nesting site in Broad Sound Islands National Park, Queensland, Australia, in the mid-2000s. Initial attempts to remove the population through ground and aerial culling (2007–2017) were unsuccessful. A more comprehensive eradication program commenced in 2018, employing aerial culling. In late 2019, a grid of 4...