R. Marsden results 41
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Soil organic carbon (SOC) sequestration is vital for food security and climate mitigation. However, its long‐term response to fertilisation remains unclear. Using the 180‐year Broadbalk Experiment (the world's longest‐running fertilisation trial; Rothamsted, UK), combined with 14 C labelling and metagenomics, we identified fundamentally distinct mechanisms of SOC accumulation: a microbially mediated dual pathway under organic...
Are nitrification inhibitors effective in reducing N2O from farm-scale emission hotspots?NARA Subscribed
Livestock congregation areas are nitrous oxide (N 2 O) hot-spots and could be key areas to focus mitigation action. We tested whether combined cattle urine and fertiliser N 2 O-N emission factors (EFs) would be higher from a farm gateway area compared to a standard pasture under sub-tropical conditions, and whether the nitrification inhibitor, dimethyl pyrazole phosphate (DMPP), would lower N 2 O EFs from the gateway area. Tre...
A clear scientific and operational need exists for harmonized bioanalytical immunogenicity study reporting to facilitate communication of immunogenicity findings and expedient review by industry and health authorities. To address these key bioanalytical reporting gaps and provide a report structure for documenting immunogenicity results, this cross-industry group was formed to establish harmonized recommendations and a develop...
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
Meta‐analysis of global livestock urine‐derived nitrous oxide emissions from agricultural soilsNARA Subscribed
Nitrous oxide (N 2 O) is an air pollutant of major environmental concern, with agriculture representing 60% of anthropogenic global N 2 O emissions. Much of the N 2 O emissions from livestock production systems result from transformation of N deposited to soil within animal excreta. There exists a substantial body of literature on urine patch N 2 O dynamics, we aimed to identify key controlling factors influencing N 2 O emissi...