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Quantity discrimination, decision-making, and the role of early-life conditions in a lizardNARA Subscribed
Quantity discrimination affects a range of behaviours essential for fitness, including social interactions, navigation, and foraging and is widespread across animal taxa. However, in reptiles, evidence for this ability — particularly for small number contrasts — remains limited and mixed. Early-life conditions, such as hormonal exposure and temperature, can also shape brain development and cognitive performance, potentially af...
Biomass dynamics of primary producers provide a basis for assessing their capacity to capture carbon and mitigate excess greenhouse gases. Here, we estimate inter-annual and seasonal biomass cycles in canopy-forming Sargassaceae at 19 sites spanning ~ 200 km of the Ningaloo World Heritage Area over 11 consecutive years. Our global average summer estimate of 1.53 kg wet wt m −2 equates to 4.1–9.4 Gg of standing macroalgal carbo...
The United Kingdom is an important wintering ground for millions of waterbirds. Most U.K. wintering waterbird populations increased between 1970 and the mid‐1990s, but declined thereafter. We examined U.K. population indices in 46 wintering waterbird species in two 25‐year periods, 1970–1994 and 1995–2019, to identify which waterbird groups were vulnerable to declines. We modeled abundance to examine whether spatial patterns i...
Forecasts of vulnerability to climate warming require an integrative understanding of how species are exposed to, are damaged by, and recover from thermal stress in natural environments. The sensitivity of species to temperature depends on the frequency, duration, and magnitude of thermal stress. Thus, there is a generally recognized need to move beyond physiological metrics based solely on critical thermal limits and integrat...
Spatial ecology and population dynamics of brown trout Salmo trutta L. in reservoirs and headwater tributariesNARA Subscribed
This investigation compared the spatial ecology and population dynamics of brown trout Salmo trutta L. between reservoirs with (impact; Langsett Reservoir) and without (control; Grimwith Reservoir) barriers to fish movements into headwater tributaries, and the effectiveness of a fish pass intended to remediate connectivity. Passive integrated transponder (PIT) telemetry revealed that fish that emigrated from Langsett and Grimw...
The Breeding Bird Survey of the United KingdomNARA Subscribed
Motivation Information on species' population trends is essential to assess species' conservation status, make informed environmental decisions and ultimately reduce biodiversity loss. Robust population trends require a long‐term monitoring programme, often using citizen scientists, that ideally generates representative and unbiased data from the study area. Here we present the dataset of the Breeding Bird Survey, the main sch...
Importance of timely metadata curation to the global surveillance of genetic diversityNARA Subscribed
Genetic diversity within species represents a fundamental yet underappreciated level of biodiversity. Because genetic diversity can indicate species resilience to changing climate, its measurement is relevant to many national and global conservation policy targets. Many studies produce large amounts of genome‐scale genetic diversity data for wild populations, but most (87%) do not include the associated spatial and temporal me...
Multiple system atrophy (MSA) is a fatal neurodegenerative disease of unknown etiology characterized by widespread aggregation of the protein alpha-synuclein in neurons and glia. Its orphan status, biological relationship to Parkinson’s disease (PD), and rapid progression have sparked interest in drug development. One significant obstacle to therapeutics is disease heterogeneity. Here, we share our process of developing a clin...
Sequencing exomes/genomes have been successful for identifying recessive genes; however, discovery of dominant genes including deafness genes (DFNA) remains challenging. We report a new DFNA gene, ATP11A , in a Newfoundland family with a variable form of bilateral sensorineural hearing loss (SNHL). Genome-wide SNP genotyping linked SNHL to DFNA33 (LOD = 4.77), a locus on 13q34 previously mapped in a German family with variable...
Excavating FAIR Data: the Case of the Multicenter Animal Spinal Cord Injury Study (MASCIS), Blood Pressure, and Neuro-RecoveryNARA Subscribed
Meta-analyses suggest that the published literature represents only a small minority of the total data collected in biomedical research, with most becoming ‘dark data’ unreported in the literature. Dark data is due to publication bias toward novel results that confirm investigator hypotheses and omission of data that do not. Publication bias contributes to scientific irreproducibility and failures in bench-to-bedside translati...
The Toxicology Investigators Consortium 2020 Annual ReportNARA Subscribed