As purifying selection becomes less effective and inbreeding increases, small populations frequently develop an increased load of genome‐wide deleterious mutations. Reflecting this pattern, deleterious mutations in genes associated with fertility and immunity have previously been identified in the cheetah ( Acinonyx jubatus ), which has had a low effective population size for at least the last 10,000 years. However, the distri...

Repulsive guidance molecule A (RGMa) is an inhibitor of neuronal growth and survival which is upregulated in the damaged central nervous system following acute spinal cord injury (SCI), traumatic brain injury, acute ischemic stroke (AIS), and other neuropathological conditions. Neutralization of RGMa is neuroprotective and promotes neuroplasticity in several preclinical models of neurodegeneration and injury including multiple...

For health and impact studies of water systems, monitoring underwater environments is essential, for which multi-frequency single- and multibeam echosounders are commonly used state-of-the-art technologies. However, the current scarcity of sediment reference datasets of both bottom backscatter angular response and water column scattering hampers empirical data interpretation. Comprehensive reference data derived from measureme...

The entire mitochondrial genome of the striped bass Morone saxatilis was sequenced together with the mitochondrial (mt) control regions of the white bass Morone chrysops , white perch Morone americana , yellow bass Morone mississippiensis , spotted seabass Dicentrarchus punctatus, European seabass Dicentrarchus labrax and the Japanese seabass Lateolabrax japonicus . The resultant 17 580 base pair circular genome of M. saxatili...