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Motor-like Tics are Mediated by CB2 Cannabinoid Receptor-dependent and Independent Mechanisms Associated with Age and SexNARA Subscribed
Δ 9 -Tetrahydrocannabinol (Δ 9 -THC) inhibits tics in individuals with Tourette syndrome (TS). Δ 9 -THC has similar affinities for CB 1 /CB 2 cannabinoid receptors. However, the effect of HU-308, a selective CB 2 receptor agonist, on repetitive behaviors has not been investigated. The effects of 2,5-dimethoxy-4-iodoamphetamine (DOI)-induced motor-like tics and Δ 9 -THC were studied with gene analysis. The effects of HU-308 on...
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