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Traumatic brain injury (TBI) is a leading cause of morbidity and mortality worldwide, with few treatment options to mitigate secondary injury. Neutrophil extracellular traps (NETs) may present a potential target for therapy. The systematic review objectives were to characterise NET formation as a feature following TBI; assess the effect of NET modulatory strategies on outcomes; and investigate the relative efficacy of NET modu...
Waterborne conspecific cues enhance larval settlement in the invasive jellyfish Aurelia coeruleaNARA Subscribed
Gregarious settlement contributes to the formation of jellyfish polyp aggregations, but the mechanism by which larvae detect habitats with conspecifics is poorly understood. Here, we tested the hypothesis that Aurelia coerulea larvae settle gregariously by detecting organic compounds released into the water by polyps. First, we conducted choice experiments to confirm the preference of larvae for substrate with conspecifics and...
Predation by the Native Nudibranch Austraeolis ornata on the Introduced Jellyfish Aurelia coeruleaNARA Subscribed
Understanding how non‐native scyphozoan jellyfish interact with native communities provides insights into the ecological processes structuring their populations. Aurelia coerulea is a problematic invasive species, with no known predators of the polyp stage outside its native range. Austraeolis ornata is a potential predator of A. coerulea polyps, but little is known about its biology and ecology. Both species inhabit shallow c...
Stony coral tissue loss disease (SCTLD) has spread throughout Florida’s Coral Reef, causing extensive mortality of over 30 species of reef-building corals, and has rapidly spread to many other countries and territories throughout the Caribbean. Current treatments for SCTLD, including a proprietary paste mixed with the antibiotic amoxicillin, do not provide protection from future infections and may select for antibiotic-resista...
With the advent of semiochemical-based control strategies used to mitigate damage of agricultural pest moths, many studies have focused on the function of male-specific putative pheromone receptors (PRs). In this investigation, we instead isolated, heterologously expressed, and functionally characterized a female-biased candidate PR, CpomOR22, from the codling moth, Cydia pomonella . Using transgenic Drosophila melanogaster fo...
Seventy five percent of the world's food crops benefit from insect pollination. Hence, there has been increased interest in how global change drivers impact this critical ecosystem service. Because standardized data on crop pollination are rarely available, we are limited in our capacity to understand the variation in pollination benefits to crop yield, as well as to anticipate changes in this service, develop predictions, and...
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
Stony coral tissue loss disease (SCTLD) has persisted since 2014 in the Southeast Florida Coral Reef Ecosystem Conservation Area (Coral ECA) where it was first discovered. Most of the highly susceptible corals have perished, leaving Montastraea cavernosa as the most abundant reef-building species with high SCTLD prevalence. Disease interventions (DI) have been conducted throughout Florida’s Coral Reef to save the remaining cor...
Collisions with buildings cause up to 1 billion bird fatalities annually in the United States and Canada. However, efforts to reduce collisions would benefit from studies conducted at large spatial scales across multiple study sites with standardized methods and consideration of species‐ and life‐history‐related variation and correlates of collisions. We addressed these research needs through coordinated collection of data on...
Enduring sustainability challenges requires a new model of collective leadership that embraces critical reflection, inclusivity and care. Leadership collectives can support a move in academia from metrics to merits, from a focus on career to care, and enact a shift from disciplinary to inter- and trans-disciplinary research. Academic organisations need to reorient their training programs, work ethics and reward systems to enco...
Wrestling with the complexity of evaluation for organizations at the boundary of science, policy, and practiceNARA Subscribed
Boundary organizations are situated between science, policy, and practice and have a goal of supporting communication and collaboration among these sectors. They have been promoted as a way to improve the effectiveness of conservation efforts by building stronger relationships between scientists, policy makers, industry, and practitioners (Cook et al. 2013). Although their promise has been discussed in theory, the work of and...