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Behavioral variation across multiple phases of intravenous cocaine self-administration among genetically diverse mouse populationsNARA Subscribed
Genetic and other predisposing factors can influence the progression from initiation of drug intake to compulsive substance use through distinct biobehavioral processes. Operant cocaine self-administration studies in laboratory mice offer a powerful method to dissect the biology of this progression from initiation, dose-response, extinction, and cued reinstatement in a controlled, tractable system. However, many such studies e...
SNAPSHOT USA 2024: Year 6 of the Coordinated National Camera Trap Survey of the United StatesNARA Subscribed
Motivation SNAPSHOT USA is an annual, multi‐contributor camera trap survey of mammals across the United States. The growing SNAPSHOT USA dataset is intended for tracking the spatial and temporal responses of mammal populations to changes in land use, land cover and climate. These data will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, as well as the impacts of speci...
The emergence of infectious diseases is often associated with changes to host–pathogen ecology, and wildfires are known to profoundly modify the ecology of terrestrial and freshwater ecosystems. Nevertheless, few studies have employed manipulative experiments to quantify the effects of fire on infections across parasite species. In a mark–recapture study, prescribed burns did not significantly affect the densities of Cuban tre...
Elevated Contact Stresses Compromise Activity-Mediated Cartilage Rehydration but not LubricationNARA Subscribed
Purpose Understanding how obesity—a key risk factor for osteoarthritis—effects articular cartilage function is critical to understand OA pathoetiology. Cartilage, a biphasic material, supports vanishingly low friction coefficients in vivo, but is tribomechanically compromised by load-induced interstitial pressure/lubrication loss. To maintain tribomechanical function, cartilage must recover fluid lost to habitual/average conta...