There is a diverging perception of climate tipping points, abrupt changes and surprises in the scientific community and the public. While such dynamics have been observed in the past, e.g., frequent reductions of the Atlantic meridional overturning circulation during the last ice age, or ice sheet collapses, tipping points might also be a possibility in an anthropogenically perturbed climate. In this context, high impact—low l...

A clear scientific and operational need exists for harmonized bioanalytical immunogenicity study reporting to facilitate communication of immunogenicity findings and expedient review by industry and health authorities. To address these key bioanalytical reporting gaps and provide a report structure for documenting immunogenicity results, this cross-industry group was formed to establish harmonized recommendations and a develop...

The Placerias /Downs’ Quarry complex in eastern Arizona, USA, is the most diverse Upper Triassic vertebrate locality known. We report a new short-faced archosauriform, Syntomiprosopus sucherorum gen. et sp. nov., represented by four incomplete mandibles, that expands that diversity with a morphology unique among Late Triassic archosauriforms. The most distinctive feature of Syntomiprosopus gen. nov. is its anteroposteriorly sh...

Six major groups of trilobites from the Silurian and Devonian of Japan are evaluated for their paleobiogeographical signature. Silurian illaenids and scutelluids show four generic‐level and at least two species‐level links with the Australian segment of the Gondwana paleocontinent; encrinurids also indicate two generic‐level links with Australia and also the South China paleocontinent; whilst Devonian phacopids, and possibly p...

Aim This paper describes a set of integrative scenarios developed in the ALARM (Assessing LArge‐scale environmental Risks for biodiversity with tested Methods) project. The ultimate aim of ALARM was to develop and test methods and protocols for the assessment of large‐scale environmental risks to biodiversity and to evaluate mitigation options. Scenarios provide a tool for exploring such risks and the policy options to mitigat...

The influence of spatial and temporal variations in wind forcing on the circulation in lakes is investigated using field data and the three‐dimensional Estuary and Lake Computer Model (ELCOM) applied to Lake Kinneret. Lake Kinneret field data from six thermistor chains and eight wind anemometers deployed during July 2001 are presented. Internal wave motions are well reproduced by the numerical model when forced with a spatiall...