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Expanding insights into plant rhabdovirus diversity through the discovery of viruses representing 32 putative novel speciesNARA Subscribed
Plant-infecting rhabdoviruses (family Rhabdoviridae , subfamily Betarhabdovirinae ) include several viruses that cause important crop diseases and are subject to phytosanitary regulation. Despite their agricultural and ecological importance, the diversity of plant rhabdoviruses and their impact on plant health remain poorly understood. Here, we report 32 tentative novel species of plant-infecting rhabdoviruses, identified via...
The Seaward Migration of European Eel at a Continental Scale: A Europe‐Wide Biotelemetry Meta‐AnalysisNARA Subscribed
The European eel ( Anguilla anguilla L.) has a catadromous life cycle, with a single panmictic population that colonises continental Europe and northern Africa yet migrates 5000 to 9000 km to spawn in the Atlantic Ocean. It is unknown how this continental migration is organised so individual eels arrive in time for spawning with conspecifics. This meta‐analysis combined tracking data from 18 water bodies in freshwater and tran...
Long‐Term Soil Warming Drives Different Belowground Responses in Arbuscular Mycorrhizal and Ectomycorrhizal TreesNARA Subscribed
The ability of trees to acquire soil nutrients under future climate conditions will influence forest composition and function in a warmer world. Rarely are multiple belowground carbon allocation pathways measured simultaneously in large global change experiments, restricting our understanding of how trees may shift their allocation of resources to different nutrient acquisition mechanisms under future climates. Leveraging a 20...
Convergence Research and Training in Computational Bioengineering: A Case Study on AI/ML-Driven Biofilm–Material Interaction DiscoveryNARA Subscribed
Historically, research disciplines have successfully operated independently. However, the emergence of transdisciplinary research has led to convergence methodologies, resulting in groundbreaking discoveries. Despite the benefits, graduate programs face challenges in implementing transdisciplinary research and preparing students for real-world collaboration across diverse disciplines and experience levels. We propose a converg...
Biodistribution of Drug/ADA Complexes: The Impact of Immune Complex Formation on Antibody DistributionNARA Subscribed
The clinical use of therapeutic monoclonal antibodies (mAbs) for the treatment of cancer, inflammation, and other indications has been successfully established. A critical aspect of drug-antibody pharmacokinetics is immunogenicity, which triggers an immune response via an anti-drug antibody (ADA) and forms drug/ADA immune complexes (ICs). As a consequence, there may be a reduced efficacy upon neutralization by ADA or an accele...
Camp Lejeune Marine Cancer Risk Assessment for Exposure to Contaminated Drinking Water From 1955 to 1987NARA Subscribed
This study utilizes guidance from the United States Environmental Protection Agency (USEPA) and the Agency for Toxic Substances and Disease Registry (ATSDR) to calculate the cancer risk to United States Marines who were exposed to carcinogens in drinking water at Marine Corps Base Camp Lejeune. Camp Lejeune is a 233-square-mile Marine Corps training facility in North Carolina. From 1953 to 1987, nearby dry cleaners, landfills,...