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Thermokarst lake and drained lake basin (DLB) dynamics are intensifying across the Alaskan Arctic Coastal Plain. Thawing, drainage, and erosion expose surface and deep sediments (> 1 m) to aerobic conditions, with saline deposits being particularly vulnerable due to freeze‐point depression. As organic carbon mineralization remains poorly constrained, we determined potentials with an aerobic one‐year long incubation at 10°C in...
2-Desaza-annomontine (C81) impedes angiogenesis through reduced VEGFR2 expression derived from inhibition of CDC2-like kinasesNARA Subscribed
Angiogenesis is a crucial process in the progression of various pathologies, like solid tumors, wet age-related macular degeneration, and chronic inflammation. Current anti-angiogenic treatments still have major drawbacks like limited efficacy in diseases that also rely on inflammation. Therefore, new anti-angiogenic approaches are sorely needed, and simultaneous inhibition of angiogenesis and inflammation is desirable. Here,...
Neurotoxic esteraseNARA Subscribed
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