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Endoplasmic reticulum aminopeptidases (ERAP) facilitate antigen presentation. Variation in ERAP1 and ERAP2 genes underwent selection during the Black Death and impact autoimmune disease susceptibility. We assess the burden of functionally impactful variants present in ERAP1 and ERAP2 in 2 cohorts of patients diagnosed with inflammatory bowel disease (IBD; Crohn’s disease (CD) or ulcerative colitis (UC)). We analysed the Southa...
Precision measurement of the Ds*+-Ds+ meson mass differenceNARA Subscribed
The SPoRC Stock Assessment Package: A Generalized Next‐Generation Platform to Assess Spatial, Age and Sex‐Structured PopulationsNARA Subscribed
Fisheries managers increasingly rely on stock assessment models to provide sustainable management advice, which must balance complex and competing objectives. Although assessment models necessitate simplifying assumptions, there is increasing recognition to improve the integration of realistic biological and fishery dynamics. While ongoing and future development of increasingly complex stock assessments requires increased capa...
The Fukushima Daiichi Nuclear Power Plant accident released radionuclides directly into the ocean as a result of the Great East Japan Earthquake on March 11, 2011. This material has been transported across the Pacific Ocean and detected in the northeastern Pacific. We began a surface ocean 129 I monitoring program a few months after this disaster in June 2011, with samples from Scripps Pier, La Jolla, California, USA, with the...
SNAPSHOT USA 2024: Year 6 of the Coordinated National Camera Trap Survey of the United StatesNARA Subscribed
Motivation SNAPSHOT USA is an annual, multi‐contributor camera trap survey of mammals across the United States. The growing SNAPSHOT USA dataset is intended for tracking the spatial and temporal responses of mammal populations to changes in land use, land cover and climate. These data will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, as well as the impacts of speci...
Under the current global biodiversity crisis, there is a need for automated and noninvasive monitoring techniques that can gather large amounts of data cost‐effectively at various ecological scales, from local to large spatial scales. These data can then be analyzed to inform stakeholders and decision‐makers. One such technique is passive acoustic monitoring, which is commonly coupled with automatic identification of animal sp...
Marine species and associated fisheries demonstrate complex spatial dynamics driven by biological, ecosystem and socioeconomic factors and integrating these spatial dynamics into stock assessment models can improve fishery management advice. While preliminary good practices for developing spatial stock assessment models have been proposed, comprehensive demonstrations applying these practices remain limited. Drawing on these g...
Multi-instrument sounding of a Jovian thunderstorm from JunoNARA Subscribed
Systematics and evolutionary history of raft and nursery‐web spiders (Araneae: Dolomedidae and Pisauridae)NARA Subscribed
Pisauridae are a global and heterogeneous assemblage of spider genera with diverse morphologies and lifestyles. So far, the monophyly of Pisauridae and the inclusion of fishing spiders ( Dolomedes ) in this family have not been thoroughly tested. Here, we amend the systematics and classification of these lineages within a UCE phylogenomic framework and through a detailed morphological reappraisal. For estimations of their evol...
Sex‐specific variation in population demography and life‐history traits (e.g., growth, natural mortality) is common in many fish populations. Differences in these processes by sex can dictate population dynamics and influence how harvesters interact with the resource. Across various fisheries management systems, stock assessment models (SAMs), which mathematically represent population age and/or size structure, are widely util...
Spermidine toxicity in Saccharomyces cerevisiae due to mitochondrial complex III deficiencyNARA Subscribed
Spermidine is a naturally occurring polyamine present in all cells and is necessary for viability in eukaryotic cells. The cellular levels of spermidine decline as an organism ages, and its supplementation has been found to extend lifespan in yeast, worms, flies, mice, and human cultured cells. The lifespan extending effect of spermidine is thought to be due to its ability to induce autophagy, a turnover of cellular components...
Emergency mass disposal of milk: Options and considerationsNARA Subscribed