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Journal of Marine Science and Engineering · 2020 · Vol. 8 · Issue 8 · MDPI
This paper presents a state-dependent constitutive model for gas hydrate-bearing sediments (GHBS), considering the cementing effect for simulating the stress–strain behavior of GHBS. In this work, to consider the influence of hydrate on matrix samples in theory, some representative GHBS laboratory tests were analyzed, and it was found that GHBS has obvious state-related characteristics. At the same time, it was found that GHBS...
Neuroscience Bulletin · 2020 · Vol. 36 · Issue 7 · Springer
Purinergic receptors have been reported to be involved in brain disorders. In this study, we explored their roles and mechanisms underlying the memory impairment in rats with type 2 diabetes mellitus (T2DM). T2DM rats exhibited a worse performance in the T-maze and Morris water maze (MWM) than controls. Microglia positive for P2X purinoceptor 4 (P2X4R) in the hippocampus were reduced and activated microglia were increased in T...
Genes & Genomics · 2020 · Vol. 42 · Issue 7 · Springer
Background Hepatitis B virus (HBV) infection is a crucial medical issue worldwide. The dependence of HBV replication on host cell machineries and their co-evolutionary interactions prompt the codon usage pattern of viral genes to translation selection and mutation pressure. Objective The evolutionary characteristics of HBV and the natural selection effects of the human genome on the codon usage characteristics were analyzed to...