Malaria is a major public health burden in South Sudan, one of the most malaria-endemic countries worldwide. In 2020, approximately 2.3 million cases and 4,500 deaths were reported. This study developed and analyzed a deterministic malaria transmission model incorporating transfusion-mediated infections and distinct diurnal and nocturnal mosquito biting rates. Using surveillance data from Central Equatoria State (CES), Warrap...