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Seismic evidence of multi-stage volcanic flank collapse and refined deposit volume offshore Fogo, Cabo VerdeNARA Subscribed
Gravitational volcanic flank collapses are recurrent processes producing large-scale landslides, commonly associated with secondary instabilities and destructive tsunamis. Ocean island volcanoes are particularly prone to such failures, yet the dynamics, emplacement mechanisms, and tsunamigenic potential of gravitational collapses remain poorly constrained due to the scarcity of direct observations. The ~ 68 ka Monte Amarelo fl...
Tyrosine kinase inhibitors (TKIs) are widely used in cancer therapy yet are strongly associated with acute and chronic cardiotoxicity in patients. There is a critical need to advance our understanding of the pathophysiology that underlies TKI-mediated cardiotoxicity, and central to this is the use of reproducible and relevant preclinical models, which are employed in the evaluation of TKIs across the drug discovery pipeline. W...
Antarctic soils are unique from those found nearly anywhere else on Earth yet can still harbor a broad diversity of microorganisms able to tolerate the challenging conditions typical of the continent. For these reasons, microbiologists have been drawn to Antarctica for decades. However, our understanding of which microbes thrive in Antarctic soils and how they to do so remains limited. To help resolve these knowledge gaps, we...
The volcanic history of Mt. Etna is mainly known from studies of subaerial deposits and stratigraphy. However, little is known about the offshore deposits, which can provide a more detailed insight into geological and sedimentological processes affecting the flanks of Mt. Etna. During RV Meteor Cruise M178, eight gravity cores were taken offshore across the continental margin east of the volcanic edifice to re-evaluate the vol...
The Once and Future Fish: Assessing a Millennium of Atlantic Herring Exploitation Through Mixed‐Stock Analysis and Ancient DNANARA Subscribed
Small pelagic fish support profitable fisheries and are important for food security around the world. Yet, their sustainable management can be hindered by the indiscriminate impacts of simultaneous exploitation of fish from multiple distinct biological populations over extended periods of time. The quantification of such impacts is greatly facilitated by recently developed molecular tools—including diagnostic single nucleotide...
Temperate rocky reefs are complex habitats that support high levels of biodiversity and productivity. However, the sessile benthic communities attached to these reefs are vulnerable to climate change and local human impacts due to their limited capacity to rapidly avoid unfavourable environments. In southeastern Australia, high latitude rocky reefs face increasing threats from rapid warming, surpassing the global average. Exis...
Communicating environmental change and mitigation scenarios to stakeholders and decision-makers can be challenging. Immersive environments offer an innovative approach for knowledge transfer, allowing science-based scenarios to be discussed interactively. The use of such environments is particularly helpful for the analysis of large, multi-component geospatial datasets, as commonly employed in the classification of ecosystems....
Developing an ocean best practice: A case study of marine sampling practices from AustraliaOA Marine
Since 2012, there has been a surge in the numbers of marine science publications that use the term ‘best practice’, yet the term is not often defined, nor is the process behind the best practice development described. Importantly a ‘best practice’ is more than a documented practice that an individual or institution uses and considers good. This article describes a rigorous process to develop an ocean best practice using exampl...
Septic arthritis is a serious condition with significant morbidity and mortality, routinely diagnosed using culture. The FDA has recently approved the rapid molecular BioFire® Joint Infection Panel (BJIP) for synovial fluid. We aimed to evaluate the BJIP compared to culture and its potential use in patient management. A multicentre retrospective evaluation of BJIP was conducted in the UK and Ireland. Positive percent agreement...
Aim Megafire events generate immediate concern for wildlife and human well‐being, but their broader ecological impacts likely extend beyond individual species and single fire events. In the first mechanistic study of fire effects focussed on ecosystems, we aimed to assess the sensitivity and exposure of ecosystems to multiple fire‐related threats, placing impacts in the context of changing fire regimes and their interactions w...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
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