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Springer Nature1
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Neuroscience Bulletin1
Publication Year
20261
Rachel Utama results 1 · Newest (Page 1/1, per page 25)
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Mescaline Alters Cerebellar Function, Global Connectivity, and Frequency-Selective Acoustic Gating: A BOLD fMRI Study in Awake RatsNARA Subscribed
Neuroscience Bulletin · 2026 · Springer
Noah Cavallaro; Priya Rai; David Akins; Sima Soltanpour; Md Taufiq Nasseef; Richard J. Ortiz; Rachel Utama; Caitlyn R. Cody; Anoushka Mistry; Heather C. Brenhouse; Praveen P. Kulkarni; Craig F. Ferris
Mescaline, a 5-HT2A agonist psychedelic used ceremonially for millennia, lacks neuroimaging characterization due to its Schedule 1 status. Using pharmacological and resting-state fMRI in awake rats, we report mescaline's first comprehensive neurobiological profile. Acutely, mescaline produced cerebellar-selective BOLD suppression, suggesting functional disconnection from forebrain structures. Paradoxically, resting-state analy...
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