Cetaceans are highly adapted marine mammals whose survival depends on precise auditory and echolocation systems. Therefore, disease processes affecting these systems, including parasitic infections pose significant morbidity and may result in stranding and death. Here, we describe the pathologic and parasitological findings in an adult, male melon-headed whale ( Peponocephala electra ) stranded dead on the Brazilian coast. The...

Cetaceans are sentinels of marine ecosystem health and are increasingly exposed to protozoal pathogens. This study investigated the occurrence and molecular identity of Sarcocystidae protozoa in 159 stranded cetaceans representing 21 species along the Brazilian coast. Molecular analysis based on PCR amplification and sequencing of the sarcocystid internal transcribed spacer 1 (ITS1) region revealed infections in 14 individuals...

The geographic distribution of consumers and their resources shapes the spatial signature of trophic interactions in heterogeneous landscapes. Bees are central place foragers that consume a wide variety of plant species around their nests, thus, bee communities in urban landscapes are an opportune system for understanding intra- and interspecific spatial variation in resource use. Here, we investigated how the spatial distribu...

The environmental dissemination of antimicrobial resistance (AMR) through livestock waste represents a growing concern for human, environmental, and animal health. This study investigated how swine waste stabilization ponds (WSPs), and subsequent manure application to agricultural soils, influence bacterial community structure, antimicrobial resistance genes (ARGs), and mobile genetic elements (MGEs). Using shotgun metagenomic...

Background Giardiasis remains a globally prevalent neglected parasitic disease, and limitations associated with conventional therapies highlight the need for alternative and complementary strategies. In this context, microalgae biocompounds have emerged as promising sources of antiparasitic agents. Objective This study aims to evaluate the in vitro preliminary screening activity (vital dye exclusion). Methods Aqueous extracts...

Contemporary global migration, driven by socioeconomic instability, armed conflict, climate change, and political factors, has emerged as a major determinant of exposome reconfiguration and cardiometabolic vulnerability. Migrant populations are disproportionately exposed to cumulative environmental, psychosocial, behavioral, and cultural stressors that may contribute to chronic low-grade inflammation, neuroendocrine dysregulat...

Bacterial resistance constitutes one of the main threats to global public health, driving the search for therapeutic strategies capable of restoring the effectiveness of antimicrobials. Among the mechanisms involved, efflux pumps stand out, reducing the intracellular concentration of drugs and contributing to multidrug resistance. In this context, inhibitors of these pumps emerge as a promising approach, as they increase the i...

Surface water quality in the Quadrilátero Ferrífero, a mining province in southeastern Brazil, was evaluated by combining water quality indices (WQI), land use and land cover (LULC), and population data to identify spatial and seasonal influences on river chemistry. We analyzed 835 (rainy) and 845 (dry) samples and calculated WQI scores using established methods from the literature. The methods for calculating the WQI detected...

The northern sector of the Rio Grande do Sul Coastal Plain, southern Brazil, preserves a detailed record of Quaternary sea-level changes and coastal processes. In this study, 54 geosites were identified and characterized across 18 municipalities, including lagoon-barrier systems, dune fields, coastal ridges, abrasion caves, testimony hills, lagoons, spits, deltas, and shell mounds. These sites document the geological evolution...

Frontotemporal dementia (FTD) is a neurodegenerative disease characterized by significant clinical and genetic heterogeneity, with approximately 40% of cases linked to hereditary genetic mutations, including MAPT , GRN , and C9ORF72 . Recently, microRNAs (miRNAs) have emerged as key regulators of cellular processes related to neurodegeneration and as potential biomarkers for FTD. However, their relevance in presymptomatic stag...