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Springer Nature1
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✓Purinergic Signalling1
Publication Year
20241
Rashed Rashed results 1 · Newest (Page 1/1, per page 25)
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Journal: Purinergic Signalling ×Author: Rashed Rashed ×Clear All Filters
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Molecular mechanisms of extracellular-ATP-mediated colorectal cancer progression: Implication of purinergic receptors-mediated nucleocytoplasmic shuttling of HuRNARA Subscribed
Purinergic Signalling · 2024 · Vol. 20 · Issue 6 · Springer
Abdel-Aziz S. Shatat; Elsayed M. Mahgoup; Mohammed H. Rashed; Ibrahim G. Saleh; El-Sayed Akool
One of the leading causes of cancer-related deaths worldwide is colorectal cancer (CRC). Extracellular ATP (e-ATP) and purinergic receptors (P2R) play a central role in CRC proliferation and progression. Human antigen R (HuR) is becoming more and more understood to be essential for the expression of genes linked to cancer. The current study demonstrates that ATP can mediate CRC (Caco-2 cells) progression via induction of HuR n...
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