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Olfactory sensory neurons (OSNs) detect odorants and send electrical signals to glomeruli in the olfactory bulb. Unlike most neurons, OSNs are continuously regenerated throughout life and immature neurons contribute to odorant-evoked responses in glomeruli. However, their intrinsic excitability properties are largely unknown. Here, we used acute slices of the olfactory epithelium from neonatal OMP-GFP mice to visually identify...
Molecular features of AHDC1: insights into an overlooked gene with broad functional potentialNARA Subscribed
Despite two decades since the completion of the human genome, many genes remain poorly understood, with their functions largely unknown. Among these, AHDC1 stands out as a top-ranking gene in the SFARI database due to its role in the rare and likely underestimated neurodevelopmental disorder, Xia-Gibbs syndrome (XIGIS). First identified in 2014 by Prof. Richard A. Gibbs and his team at Baylor College of Medicine, AHDC1 has his...
Paternal starvation affects metabolic gene expression during zebrafish offspring development and lifelong fitnessNARA Subscribed
Dietary restriction in the form of fasting is a putative key to a healthier and longer life, but these benefits may come at a trade‐off with reproductive fitness and may affect the following generation(s). The potential inter‐ and transgenerational effects of long‐term fasting and starvation are particularly poorly understood in vertebrates when they originate from the paternal line. We utilised the externally fertilising zebr...
Genomewide transcriptional reprogramming in the seagrass Cymodocea nodosa under experimental ocean acidificationNARA Subscribed
Here, we report the first use of massive‐scale RNA ‐sequencing to explore seagrass response to CO 2 ‐driven ocean acidification ( OA ). Large‐scale gene expression changes in the seagrass Cymodocea nodosa occurred at CO 2 levels projected by the end of the century. C. nodosa transcriptome was obtained using Illumina RNA ‐Seq technology and de novo assembly, and differential gene expression was explored in plants exposed to sho...
Synechococcus : 3 billion years of global dominanceNARA Subscribed
Cyanobacteria are among the most important primary producers on the E arth. However, the evolutionary forces driving cyanobacterial species diversity remain largely enigmatic due to both their distinction from macro‐organisms and an undersampling of sequenced genomes. Thus, we present a new genome of a S ynechococcus ‐like cyanobacterium from a novel evolutionary lineage. Further, we analyse all existing 16 S rRNA sequences an...
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