Purpose of Review Organoid intelligence (OI) is an emerging field in biological computing that integrates brain organoids with external interfaces capable of receiving and transmitting signals. This article aims to provide an overview of the current state of organoid intelligence and its ethical and moral frameworks. A fundamental question is posed: can brain organoids connected to a computer interface be said to be endowed wi...

Purpose Recent improvements in Nanopore sequencing chemistry has made it a promising platform for long-read 16S rRNA sequencing. This study evaluated its clinical utility in a nationwide collaboration coordinated by Genomic Medicine Sweden. Methods Thirteen mock samples comprised of various bacterial strains and an External Quality Assessment (EQA) panel from QCMD (Quality Control for Molecular Diagnostics) were analysed by 20...

The North Pacific subtropical gyre is a globally important contributor to carbon uptake despite being a persistently oligotrophic ecosystem. Supply of the micronutrient iron to the upper ocean varies seasonally to episodically, and when coupled with rapid biological consumption, results in low iron concentrations. In this study, we examined changes in iron uptake rates, along with siderophore concentrations and biosynthesis po...

Decomposition of whole-brain functional connectivity patterns reveals a principal gradient that captures the separation of sensorimotor cortex from heteromodal regions in the default mode network (DMN). Functional homotopy is strongest in sensorimotor areas, and weakest in heteromodal cortices, suggesting there may be differences between the left and right hemispheres (LH/RH) in the principal gradient, especially towards its a...

Metabolites that incorporate elements other than carbon, nitrogen, hydrogen and oxygen can be selectively detected by inductively coupled mass spectrometry (ICPMS). When used in parallel with chromatographic separations and conventional electrospray ionization mass spectrometry (ESIMS), ICPMS allows the analyst to quickly find, characterize and identify target metabolites that carry nutrient elements (P, S, trace metals; “nutr...

Coastal upwelling of nutrients and metals along eastern boundary currents fuels some of the most biologically productive marine ecosystems. Although iron is a main driver of productivity in many of these regions, iron cycling and acquisition by microbes remain poorly constrained, in part due to the unknown composition of organic ligands that keep bioavailable iron in solution. In this study, we investigated organic ligand comp...

The preferential larval distributions of 22 fish species in the California Current System were identified in their temporal, spatial, and thermal domains using single parameter quotient analysis. This analysis allowed the characterization of their reproductive habitats based on ranges of preference, tolerance, and avoidance. In the temporal domain, the species’ preference intervals were wider than those previously reported, an...

31Maps depicting spatial variation in wood properties are important for forest product industries as they aid decision making regarding raw material procurement, can assist in product categorization and help improve utilization. Loblolly pine is an important commercial species grown throughout the southern Unites States of America (USA). Wood Quality Consortium (WQC)—a joint collaboration between the University of Georgia, USD...