Rodrigo Macedo results 66
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Chikungunya virus (CHIKV) is an arthropod-borne virus responsible for an acute febrile illness characterized by severe polyarthralgia, predominantly affecting peripheral joints. In a substantial proportion of patients, these symptoms may progress to chronic manifestations that significantly impair quality of life. Animal models are therefore critical for the development of effective therapeutic and preventive strategies, inclu...
Earth mounds with the presence of palms have high evolutionary history in the Cerrado–Caatinga ecotoneNARA Subscribed
The presence of palms on earth mounds may increase community phylogenetic diversity (PD) by promoting facilitation and acting as natural perches that enhance species recruitment. We investigated whether palm presence and mound size affect the phylogenetic diversity (alpha and beta) and structure of woody vegetation. We selected 42 earth mounds in an ecotone between the Cerrado and Caatinga biomes: 15 with Copernicia prunifera...
Serum Neurofilament Light Levels in Patients with Cerebrotendinous Xanthomatosis: a Pilot StudyNARA Subscribed
Introduction: Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive disorder caused by pathogenic variants in CYP27A1 , leading to cholestanol accumulation and progressive neurological dysfunction. Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in several hereditary ataxias, but its role in CTX has not been investigated. We aimed to determine whether serum NfL is elevated in CTX and whether i...
Motivation Here, we make available a second version of the BioTIME database, which compiles records of abundance estimates for species in sample events of ecological assemblages through time. The updated version expands version 1.0 of the database by doubling the number of studies and includes substantial additional curation to the taxonomic accuracy of the records, as well as the metadata. Moreover, we now provide an R packag...
Water restriction alters seed bank traits and ecology in Atlantic Forest seasonal forests under climate changeNARA Subscribed
The soil seed bank (SSB) is one of the key mechanisms that ensure the perpetuity of forests, but how will it behave in the scenarios projected for the future climate? Faced with this main question, still little explored in seasonal tropical forests, this study evaluated the germination, ecological attributes, and functional traits of the SSB in a seasonal forest in the Atlantic Forest. Forty‐eight composite samples of the SSB...