Anthropogenic habitat transformation has led to population declines and increasing isolation of populations of many species, particularly top predators, where small and fragmented populations often experience limited dispersal and reduced genetic diversity. Jaguars ( Panthera onca ), for example, have lost half of their historical range and most populations outside the Amazon biome are small, isolated and highly threatened. He...

Organotellurium (OTe) compounds have pharmacological properties, including leishmanicidal, antimalarial, and antifungal activities. Herein, we assessed cytotoxicity effects of OTe RF07 in a panel of tumor cell lines, as well as its oxidative, toxicity, and hemolytic actions. The toxicity was evaluated on Allium cepa and Artemia salina larvae. Cell viability was also assessed by resazurin in murine cells (Sarcoma 180), human ce...

Introduction Male hypogonadism, including age-related and functional forms, is characterized by insufficient testosterone production often associated with obesity and metabolic comorbidities. Testosterone replacement therapy (TRT) increases serum testosterone but suppresses spermatogenesis and may cause adverse effects. Selective estrogen receptor modulators (SERMs), such as clomiphene citrate, have emerged as an alternative a...

Developmental and eruption abnormalities are common and can result in progressive dental diseases. Ectopic eruption of the affected tooth may be the result of these processes. This study aims to report the occurrence of a permanent mandibular tooth in a horizontal position, with retention of the corresponding deciduous tooth, in a miniature horse. A 2-year-old female miniature horse was admitted to the veterinary hospital with...

Phytoplankton and zooplankton organisms are important constituents of the Antarctic marine food-web and play important roles in carbon export. This study analysed the composition and vertical distribution of zooplankton in association with phytoplankton community composition over a 20 h in February 2017 at a fixed station in the central basin of the Bransfield Strait. The water column was stratified, resulting in the dominance...

Fipronil is a widely used agricultural insecticide associated with the contamination of apiculture products and honeybee mortality. This study evaluated the presence of fipronil in honey samples from conventional and agroecological apiaries in Paraná, Brazil, and its toxic effects on Africanized Apis mellifera bees. Honey from four conventional apiaries showed fipronil levels above the maximum residue limit (0.05 µg mL −1 ), w...

Extracting coarse-resolution river drainage networks from fine-resolution DEM or DTM is essential for large-scale hydrological and environmental modeling. Flow direction upscaling methods are preferred for preserving drainage patterns, but they face significant computational challenges when handling massive fine-resolution datasets. This study introduces eCOTAT + , an enhanced version of the COTAT + algorithm, designed to impr...

Although some effects of glucocorticoids are necessary for metabolic responses during stress, chronic exposure to high levels of these hormones can cause side effects such as hyperglycemia, insulin resistance, and muscle atrophy. Elevated glucocorticoid levels are observed in several clinical conditions, and their exogenous administration, such as high-dose dexamethasone treatments, is included in many clinical protocols. In t...