Sporotrichosis is a globally distributed subcutaneous mycosis caused by fungi belonging to the Sporothrix genus. The limitations of current treatment options for sporotrichosis have driven an urgent search for new antifungal drugs. Diphenyl diselenide (PhSe)₂, a stable organoselenium, has promising activity against Sporothrix spp. Since chemical modifications in molecules can enhance their antifungal properties, this study aim...

Although microplastics (MPs) and polycyclic aromatic hydrocarbons (PAHs) are widespread in aquatic environments, their combined effects in freshwater systems remain poorly understood. This gap is relevant because green algae, frequently exposed to MPs, play an important role in PAHs bioremediation. This study evaluated how MPs influence the toxicity of benzo[a]pyrene (BaP) in the green microalga Raphidocelis subcapitata . A fu...

The objective of the present study was to evaluate the effects of the genetic merit for backfat thickness (GMB) and subcutaneous fat thickness (FT) on meat quality traits of Nellore and crossbred (½ Aberdeen Angus + ½ Nellore) steers. The animals were obtained by mating Nellore cows with Nellore or Aberdeen Angus bulls. Both paternal genetic groups were selected to provide positive (+, high GMB) or negative (-, low GMB) expect...

Organotellurium (OTe) compounds have pharmacological properties, including leishmanicidal, antimalarial, and antifungal activities. Herein, we assessed cytotoxicity effects of OTe RF07 in a panel of tumor cell lines, as well as its oxidative, toxicity, and hemolytic actions. The toxicity was evaluated on Allium cepa and Artemia salina larvae. Cell viability was also assessed by resazurin in murine cells (Sarcoma 180), human ce...

Euterpe edulis Martius (juçara palm) is an endangered species of high ecological and economic importance. Its propagation via reproduction is limited by the recalcitrance of its seeds, which hinders conservation and genetic improvement. Somatic embryogenesis represents an efficient alternative for large-scale clonal propagation and conservation. The present study evaluated the effect of abscisic acid (ABA) on histodifferentiat...

Euterpe edulis is of ecological and economic relevance and is currently threatened with extinction. Its vulnerability to extinction, combined with the recalcitrant nature of its seeds, justifies the search for alternative reproduction techniques. Somatic embryogenesis is an alternative propagation method that is subdivided into distinct phases. Maturation is a crucial phase in the process for the successful regeneration of som...