Site fidelity is the tendency for animals to repeatedly return to the same locations, either within or between years. Site fidelity enables animals to utilize knowledge of previously visited locations, including assessments of seasonal variations in health and mortality risks (e.g., predation), resource availability, and social benefits such as pairing with previous mates. However, rigidly enacted site fidelity may come with f...

The geroscience hypothesis proposes that underlying biological processes, such as the accumulation of senescent cells, have deleterious effects on multiple tissues and increase the risk of many chronic conditions with aging. Senescent cells produce heterogenous biomarkers, also called senescence-associated secretory phenotype (SASP). Circulating concentrations of senescence biomarkers may reflect an underlying burden of senesc...

Cellular senescence is a plausible mediator of age-associated declines in physical performance. To test this premise, we examined cross-sectional associations between circulating components of the senescence-associated secretory phenotype (SASP) and measures of physical function and muscle strength in 1377 older adults. We showed significant associations between multiple SASP proteins and the short physical performance battery...