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Roger Cone results 4 · Newest (Page 1/1, per page 25)
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CRISPR/Cas9-mediated knock-in of masu salmon (Oncorhyncus masou) elongase gene in the melanocortin-4 (mc4r) coding region of channel catfish (Ictalurus punctatus) genomeNARA Subscribed
Transgenic Research · 2023 · Vol. 32 · Issue 4 · Springer
Michael Coogan; De Xing; Baofeng Su; Veronica Alston; Andrew Johnson; Mohd Khan; Karim Khalil; Ahmed Elaswad; Shangjia Li; Jinhai Wang; Cuiyu Lu; Wenwen Wang; Darshika Hettiarachchi; Mei Shang; Tasnuba Hasin; Zhenkui Qin; Roger Cone; Ian A. E. Butts; Rex A. Dunham
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Editing the Melanocortin-4 Receptor Gene in Channel Catfish Using the CRISPR-Cas9 SystemOA Marine
Fishes · 2023 · Vol. 8 · Issue 2 · MDPI
Karim Khalil; Ahmed Elaswad; Hisham Abdelrahman; Maximillian Michel; Wenbiao Chen; Shikai Liu; Ramjie Odin; Zhi Ye; David Drescher; Khoi Vo; William S. Bugg; Guyu Qin; Yujia Yang; Nathan J. C. Backenstose; Zhanjiang Liu; Roger D. Cone; Rex Dunham
The melanocortin-4 receptor (MC4R) plays a critical role in homeostasis and the regulation of body weight. Polymorphisms in the mc4r gene have been discovered and linked to growth, carcass composition, and meat quality traits. Therefore, we used the CRISPR-Cas9 system to target the mc4r gene in the most important freshwater aquaculture species in the USA, channel catfish, Ictalurus punctatus. Guide RNAs were designed to direct...
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Improved Growth and High Inheritance of Melanocortin-4 Receptor (mc4r) Mutation in CRISPR/Cas-9 Gene-Edited Channel Catfish, Ictalurus punctatusNARA Subscribed
Marine Biotechnology · 2022 · Vol. 24 · Issue 5 · Springer
Michael Coogan; Veronica Alston; Baofeng Su; Karim Khalil; Ahmed Elaswad; Mohd Khan; Andrew Johnson; De Xing; Shangjia Li; Jinhai Wang; Rhoda M. C. Simora; Cuiyu Lu; Patrick Page-McCaw; Wenbiao Chen; Max Michel; Wenwen Wang; Darshika Hettiarachchi; Tasnuba Hasin; Ian A. E. Butts; Roger D. Cone; Rex A. Dunham
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Molecular and pharmacological characterization of dominant black coat color in sheepNARA Subscribed
Mammalian Genome · 1999 · Vol. 10 · Issue 1 · Springer
Dag Inge Våge; Helge Klungland; Dongsi Lu; Roger D. Cone
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