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Cynoglossus semilaevis parvovirus (CsPV) is an important pathogen that poses a serious threat to the aquaculture industry. In the absence of vaccines and effective therapeutic drugs, early and sensitive detection of the pathogen is the key measure to prevent and control the outbreaks and epidemics of viral diseases. Currently, the existing detection methods for CsPV are expensive and rely on specialized operations, limiting th...
FOXG1 Transcriptionally Orchestrates Parvalbumin+ Interneuron Function Contributing to Schizophrenia PathologyNARA Subscribed
Schizophrenia (SCZ) is characterized by heterogeneous symptoms including abnormal perception, social withdrawal, and cognitive deficits. Parvalbumin-positive (PV + ) interneurons are particularly vulnerable in SCZ; however, the underlying cellular basis remains unclear. In this study, we found that selective deletion of the SCZ risk gene Foxg1 in PV + interneurons of mice recapitulated aspects of the disease phenotype, includi...