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Condition Does Not Alter Responsiveness to Mating Signals in Female Pacific Field CricketsNARA Subscribed
Animals often vary in their condition (i.e. the amount of resources allocatable to fitness-related functions) and such variation can influence the expression of important mating behaviors like how quickly individuals respond to mating signals. If individuals in poor condition invest less in finding mates, perhaps because they can’t afford the energetic costs, then variation in condition could weaken selection on sexual signals...
Modulatory effects of bioactive natural compounds on pruritic pathways: mechanistic basis and therapeutic prospectsNARA Subscribed
Chronic pruritus, characterized by persistent itching, is a significant health issue that adversely affects individuals’ quality of life, particularly in palliative care environments. Conventional treatments frequently do not yield sufficient relief and may lead to undesirable side effects, which has spurred interest in exploring alternative therapeutic options. A thorough literature search was conducted across several databas...
Making the Most of Available Data: A Case Study of Converging Analyses to Model an Emerging Fishery for Jonah Crab ( Cancer borealis )NARA Subscribed
Targeted fishing of Jonah crabs ( Cancer borealis ) has greatly intensified in recent decades as lobster populations have declined, forcing fishermen to shift their focus to Jonah and other crab species. Effective management of this developing fishery is limited, however, by a lack of information on their life history traits, abundance and distribution. The long‐term sustainability of the fishery depends upon near‐term efforts...
Substrate stiffness dictates unique paths towards proliferative arrest in WI-38 cellsNARA Subscribed
Finite replicative potential is a defining feature of non-transformed somatic cells, first established by Leonard Hayflick in vitro using WI-38 human lung fibroblasts. Once proliferative capacity is exhausted due to telomere shortening, cells enter into a state called replicative senescence, which can be avoided through ectopic expression of telomerase reverse transcriptase (hTERT). As WI-38 cells approach replicative arrest,...
Response to Article Commentary by Ranjana Sah and colleaguesNARA Subscribed