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NARA Subscribed2
Publisher
Springer Nature2
Journal
✓GeroScience2
Publication Year
20242
Rui-Rui He results 2 · Newest (Page 1/1, per page 25)
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Journal: GeroScience ×Author: Rui-Rui He ×Clear All Filters
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Whole exome sequencing analyses reveal novel genes in telomere length and their biomedical implicationsNARA Subscribed
GeroScience · 2024 · Vol. 46 · Issue 5 · Springer
Wei-Shi Liu; Bang-Sheng Wu; Liu Yang; Shi-Dong Chen; Ya-Ru Zhang; Yue-Ting Deng; Xin-Rui Wu; Xiao-Yu He; Jing Yang; Jian-Feng Feng; Wei Cheng; Yu-Ming Xu; Jin-Tai Yu
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Endothelial specific prolyl hydroxylase domain-containing protein 2 deficiency attenuates aging-related obesity and exercise intoleranceNARA Subscribed
GeroScience · 2024 · Vol. 46 · Issue 4 · Springer
Lihong Pan; Xiaochen He; Rui Xu; Umesh Bhattarai; Ziru Niu; Jussara do Carmo; Yuxiang Sun; Heng Zeng; John S. Clemmer; Jian-Xiong Chen; Yingjie Chen
Obesity and exercise intolerance greatly reduce the life quality of older people. Prolyl hydroxylase domain-containing protein 2 (PHD2) is an important enzyme in modulating hypoxia-inducible factor-alpha (HIF) protein. Using vascular endothelial cell-specific PHD2 gene knockout (PHD2 ECKO) mice, we investigated the role of endothelial PHD2 in aging-related obesity and exercise capacity. Briefly, PHD2 ECKO mice were obtained by...
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