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Springer Nature1
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✓GeroScience1
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20241
Rui-Rui Li results 1 · Newest (Page 1/1, per page 25)
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Journal: GeroScience ×Author: Rui-Rui Li ×Clear All Filters
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Benefits of calorie restriction in mice are mediated via energy imbalance, not absolute energy or protein intakeNARA Subscribed
GeroScience · 2024 · Vol. 46 · Issue 5 · Springer
Daniel L. Smith; Sharon E. Mitchell; Maria S. Johnson; Victoria K. Gibbs; Stephanie Dickinson; Beate Henschel; Rui Li; Kathryn A. Kaiser; Daniella E. Chusyd; Andrew W. Brown; David B. Allison; John R. Speakman; Tim R. Nagy
Caloric restriction (CR) results in reduced energy and protein intake, raising questions about protein restriction’s contribution to CR longevity benefits. We kept ad libitum ( AL )–fed male C57BL/6J mice at 27°C (AL27) and pair-fed (PF) mice at 22°C (22(PF27)). The 22(PF27) group was fed to match AL27 while restricted for calories due to cold-induced metabolism. The 22(PF27) mice had significantly lower body weight, lean mass...
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