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Genetic and Phenotypic Spectrum of Amyotrophic Lateral Sclerosis Patients with CCNF Variants from a Large Chinese CohortNARA Subscribed
Cyclin F (CCNF) variants have been found to be associated with amyotrophic lateral sclerosis (ALS)/frontotemporal dementia (FTD). However, the genetic and clinical characteristics of ALS patients who carry CCNF variants are largely unknown. Genetic analysis was performed for 1587 Chinese ALS patients, and missense variants were predicted by software analyses. Additionally, we searched PubMed, Embase, and Web of Science for rel...
Diversity, evolution and life strategies of CbK ‐like phagesNARA Subscribed
Caulobacter phage CbK has been extensively studied as a model system in virology and bacteriology. Lysogeny‐related genes have been found in each CbK‐like isolate, suggesting a life strategy of both lytic and lysogenic cycles. However, whether CbK‐related phages can enter lysogeny is still undetermined. This study identified new CbK‐like sequences and expanded the collection of CbK‐related phages. A common ancestry with a temp...
The qualit12y of shafting alignment is related to the reliability and safety of a ship’s operation, and bearing displacement adjustment (BDA) plays a key role in shafting alignment. To solve the problems encountered in ship shafting alignment in the actual construction, this study focused on the investigation of the shafting load measurement system based on the strain gauge method (SGM), used the optimization method based on q...
Characteristics of drought, low temperature, and concurrent events of maize in Songliao PlainNARA Subscribed
Maize is susceptible to drought and low temperatures. In recent years, drought, low temperatures, and their composite events have often occurred during the growth period of maize, causing a huge impact. In this study, maize in the Songliao Plain was used as the research object. Based on the crop water surplus deficit index (CWSDI) and heat index (F(T)), combined with the Theil–Sen median and Mann–Kendall tests (Sen–MK) and emp...