Storm surge current-time estimations are strongly influenced by recent water-level conditions, while the temporal dependence among samples from the same typhoon event can complicate the assessment of model generalization to unseen events. This study evaluated storm surge estimation at the Lianyungang tide gauge using 2168 samples from 28 typhoon events during 2002–2024. A 41-feature extreme gradient boosting (XGBoost) model in...

This study aims to elucidate the biological effects of Baicalein (BA) on intervertebral disc degeneration (IDD) and the potential mechanisms involved. Network pharmacology analysis was performed to identify the core targets and signaling pathways responsible for the therapeutic effects of BA on IDD. In vitro validation was carried out using IL-1β-stimulated nucleus pulposus cells (NPCs). Cell viability, apoptosis, inflammatory...

Biomolecular condensates formed through phase separation have emerged as a central principle of cellular organization, enabling the dynamic regulation of gene expression, signaling, metabolism, and stress responses. While early conceptual advances in condensate biology have largely originated from animal and in vitro systems, plant cells present a unique set of biological and technical challenges, including rigid cell walls, t...