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Background The escalating prevalence of multidrug-resistant pathogens, specifically carbapenem-resistant Acinetobacter baumannii (CR-AB), underscores the urgent need for novel antimicrobial strategies. Antimicrobial peptides (AMPs) offer a viable alternative to conventional antibiotics. Methods We discovered a novel AMP, designated OAMP, from oyster hemolymph and evaluated its antimicrobial efficacy against a spectrum of patho...